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Explore your options CareerOneStop is, as the name implies, a one-stop shop for all your job search needs – and it really delivers, whether you’re exploring careers, looking for training or job hunting. Exploring?. You can take a skills assessment, identify in-demand skills, compare occupations and research industries. Looking for training?. We can help you find training opportunities from high school equivalency to short-term training to college programs.

We can also help you assess costs and find financial aid. For job hunters, we’ve got tips on resumes, networking and interviews. You can find all of these resources online, or by contacting one of the 2,320 American Job Centers around the country to learn more about their services and arrange a visit. Earn while you learn If you want to gain new skills while pulling in a paycheck, you should definitely consider an apprenticeship. You can get paid while gaining the skills, experience and credentials that employers want.

The average annual starting salary of apprenticeship grads is $72,000, and apprenticeships are available in a wide and growing variety of occupations. Sound interesting?. Learn more at apprenticeship.gov. Find a new field Maybe you’re happy with the skills you’ve got, but you’re still looking for a change. With MyNextMove.org, you can search careers by key words, browse by industry, or answer questions about the type of work you’d like to do and we’ll show you relevant job options.

Each career page includes the relevant knowledge, skills and abilities you’ll need. There’s a version of this tool in Spanish (Mi Próximo Paso) and one just for veterans (My Next Move for Veterans) that matches military classification codes with civilian careers. MySkillsMyFuture can help you find and explore new career paths. Just enter your current or past job, and we’ll provide a list of jobs with needed skillsets. Click on any that look interesting and learn more about them.

Careers begin here Job Corps offers free training and education for people ages 16-24, and is now accepting enrollment for in-person instruction. Explore and compare career paths in dozens of in-demand fields at jobcorps.gov/train. Get the details Let’s say you’ve narrowed down your options and you’re starting to wonder which one offers the best opportunities. The Bureau of Labor Statistics’ Occupational Outlook Handbook is your next stop. Select the occupational field you’re considering, and the handbook will provide tons of information, including.

Educational requirements Median annual salary Projected growth You can also browse occupations by pay, speed and size of growth and educational requirements. People are looking for work all over America. Help us connect them with good jobs by sharing this information with them!. Kim Vitelli is the administrator of the Office of Workforce Investment at the U.S. Department of Labor.

¿Busca Trabajo?. Nosotros le Podemos Ayudar Por Kim Vitelli Últimamente hemos visto mucho movimiento en el mercado laboral. En agosto hubo 10,4 millones de vacantes disponibles, se hicieron 6,3 millones de contrataciones y se registraron 4,3 millones renuncias. La tasa de abandonos aumentó en un 2.9%, el porcentaje más alto desde que comenzamos a rastrear datos. En otras palabras, hay muchos trabajos disponibles y muchas personas buscando algo nuevo.

Si usted, o alguien que conoce, está considerando un cambio de ocupación, tenemos una gran cantidad de recursos para ayudarlo a comenzar. Explore sus opciones CareerOneStop es, como su nombre indica, un lugar de arranque para todas sus necesidades de búsqueda de trabajo. Y realmente funciona, ya sea que esté explorando carreras, buscando entrenamiento o averiguando por trabajos. ¿Está explorando opciones?. Puede hacer una valoración de habilidades, identificar destrezas en demanda, comparar ocupaciones e investigar industrias.

¿Busca formación?. Podemos ayudarlo a encontrar oportunidades de capacitación desde equivalencia con la escuela secundaria a entrenamientos a corto plazo y programas universitarios. También podemos ayudarlo a evaluar costos y encontrar ayuda financiera. También tenemos consejos sobre currículums, redes de contactos y entrevistas de trabajo para los buscadores de empleo. Puede encontrar todos estos recursos en línea o comunicándose con uno de los 2.320 American Job Centers en todo el país para saber más sobre sus servicios y concertar una visita.

Gane mientras aprende Si desea adquirir nuevas habilidades al mismo tiempo que recibe un cheque de pago, definitivamente debería considerar un aprendizaje. Se le puede pagar mientras adquiere conocimientos, experiencia y credenciales que quieren los empleadores. El salario inicial promedio anual de los graduados de aprendizaje es de $72,000, y hay aprendizajes disponibles en una amplia y creciente variedad de ocupaciones. ¿Suena interesante?. Sepa más en apprenticeship.gov.

Encuentre un nuevo campo Tal vez esté satisfecho con las habilidades que tiene, pero aún está buscando un cambio. Con MyNextMove.org puede buscar carreras por palabras clave, navegar por sectores o responder preguntas sobre el tipo de trabajo que le gustaría hacer y le mostraremos opciones de trabajo relevantes a esa búsqueda. Cada página incluye los conocimientos, habilidades y destrezas clave que necesitará. Existe una versión de esta herramienta en español (Mi Próximo Paso) y otra sólo para veteranos (My Next Move for Veterans) que ajusta los códigos de clasificación militar con las carreras civiles. MySkillsMyFuture puede ayudarlo a encontrar y explorar nuevas trayectorias laborales.

Simplemente ingrese su trabajo actual o pasado, y le proporcionaremos una lista de empleos junto con las habilidades necesarias. Haga clic en cualquiera que parezca interesante y aprenda más sobre ellos. Las carreras comienzan aquí Job Corps ofrece capacitación y educación gratuitas para personas de entre 16 a 24 años, y ahora acepta inscripciones para instrucción en persona. Explore y compare trayectorias ocupacionales en docenas de campos demandados en jobcorps.gov/train. Obtenga los detalles Supongamos que ya ha concretado sus opciones y está empezando a preguntarse cuál ofrece las mejores oportunidades.

El Manual de Perspectivas Ocupacionales de la Oficina de Estadísticas Laborales es su próxima parada. Seleccione el campo ocupacional que está considerando y el manual proporcionará muchísima información, incluyendo. Requisitos educativos Salario medio anual Proyección de crecimiento También puede buscar ocupaciones por salario, ritmo y tamaño del crecimiento, y requisitos educativos. La gente está buscando trabajo por todo Estados Unidos. ¡Ayúdenos a conectarlos con buenos trabajos compartiendo esta información con ellos!.

Kim Vitelli es la administradora de la Oficina de Inversión en la Fuerza Laboral del Departamento de Trabajo de EE.UU.Cristina Barillas met Deputy Secretary of Labor Julie Su in October at an event for Latina Equal Pay Day – the day that marks how many months into the year it takes Latinas to earn the same amount as their non-Hispanic white male counterparts in the year before. We asked Cristina to share her experience as a woman who worked her way into a profession traditionally segregated by race and gender, and what that good job means to her and her family. Tell us about yourself. How did you choose this field of work?. I always find this funny when asked.

I believe plumbing choose me, not me it. It was at a point in my life when I needed a job that was more stable, and at that same time a friend suggested I try getting into the trades. In 1998 I applied to both the Electricians Local 134 IBEW and Plumbers Local 130 UA. In January of 2000, I had just reapplied for the electricians and was about to reapply to the plumbers, when I received my acceptance letter to Local 130. What is your favorite part of the job?.

This has changed over the years. I am thrilled to build something, fix something or even diagnose a problem, but it’s not just the work. What I love more is the sisterhood and brotherhood of helping my fellow plumbers succeed. That is what my motto is. €œI am here to make your journey better than mine.” What resources – job trainings, career development, etc.

€“ did you use?. I wasn’t introduced to Chicago Women in Trades (CWIT) until 2003 and since then I have always participated as much as I can. When people ask me for assistance in getting their daughter, sister or friend into plumbing, I always suggest going through CWIT Technical Opportunities Program (TOP). There is nothing like CWIT TOP. You can learn about every trade, and not only by reading or meeting a person in a trade, but hands on.

A woman can determine what trade would best suit her, and then start creating her own sister group with the other ladies in the program. CWIT is a vital organization. Besides TOP, it is a safe space for women to continue learning their trade with other sisters and a space with no fear of judgement, rejection or harassment. I have heard many sisters call CWIT “home.” We also formed Women of 130, a group specifically for Local 130 women (apprentices, journeymen or retirees). We saw a need to ensure that women could complete the program and remain in the local to finish out their career.

We have seen many sisters fall victim to the ebbs and flows of our trade, so we created an environment where our sisters felt encouraged, supported and accepted. What would you say to a woman who wants to join your industry but is hesitant?. I would tell her to get in touch with CWIT or any similar organization. If you want to start in a trade or you’re curious about the trade, this is where you start. CWIT will introduce you to the trades, they will help fill out the applications, they will help you study (for both the written and physical exam), and they will encourage you.

Plus, it’s a great way to meet women that are in the trades, doing what one day you could possibly be doing. As far as plumbing, I would tell her, “I love my trade, my sisters, my brothers, there is nothing like the fulfillment of plumbing, 'we protect the health of the nation.'” Editor's note. Chicago Women in Trades is also a WANTO grantee. Learn more about the U.S. Department of Labor's Women in Apprenticeship and Non-Traditional Occupations grant program..

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Imersis decomposes T-MSIS Top Priority propecia turkey Items (TPIs) into data quality measures and allows users to pinpoint specific issues, root out the sources of bad data, and remediate low scores before submitting data files to CMS. NewWave and Mathematica, drawing on their combined extensive experience working with the CMS and their propecia turkey deep knowledge of Medicaid data, are a uniquely suited partnership to support the Maryland Department of Health and improve the data quality of its Medicaid program. €œThe Imersis tool provides a way for states to visualize their Medicaid data quality and build a strong data analytics program,” said Jay Tanner, NewWave Program Director for Imersis.

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Sarah.rodriguez@newwave.io Todd propecia turkey Kohlhepp Email. Tkohlhepp@mathematica-mpr.comMounting real-world evidence shows universal screening for health-related social needs in routine clinical care offers a standardized way for health care providers to identify needs, tailor care, and help patients resolve these needs with referrals to community resources. Yet screening for patients’ social needs can seem propecia turkey like a daunting task for clinical providers.

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To help providers administer the screening tool, Mathematica developed, on CMS’s behalf, a set of instructions for users called “A Guide to Using the Accountable Health Communities Health-Related Social Needs Screening Tool. Promising Practices and Key Insights.”The Accountable Health Communities Health-Related Social Needs Screening Tool enables users to quickly assess patients’ social needs from five domains that CMS determined as core needs (living situation, food, transportation, utilities, and safety) and propecia turkey eight supplemental domains (financial strain, employment, family and community support, education, physical activity, substance use, mental health, and disabilities). The screening tool is appropriate for use in a wide range of clinical settings, including primary care practices, emergency departments, labor and delivery units, inpatient psychiatric units, behavioral health clinics, and other places where people access propecia turkey clinical care.

The tool is available in three versions. (1) a standard self-administered version, (2) a proxy version with questions adapted to enable someone to answer on behalf of the patient, and (3) a multiuse version that includes language for a proxy and for patients answering for themselves.After quickly identifying social needs using the screening tool, health propecia turkey care or social service providers can then connect patients with community resources to address the patients’ unmet needs.Implementing universal health-related social needs screening in clinical settings requires planning, which includes aligning priorities, training staff, and developing customized screening protocols. In light of this, the guide also includes lessons based on the experiences of organizations participating in the Accountable Health Communities Model.

The strategies shared in the propecia turkey guide are meant to inform effective universal screening in a wide range of clinical settings.Promising practices for universal screening described in the guide Cultivate staff buy-in Tailor staffing models to site features Provide dedicated training on screening Use customized scripts to engage patients in screening Consider the timing, location, and process for screening to maximize patients’ participation Anticipate population-specific needs Train staff to manage privacy and address safety concerns Institute continuous quality improvement Prepare staff to respond to common questionsFor more information on the AHC Screening Guide, please contact Lee-Lee Ellis and Rachel Kogan.The American Ballet Theatre — the country's national ballet company — has announced it will be returning to the stage in New York City this October, a year after halting indoor performances due to hair loss treatment."We cannot wait to see ABT in the Lincoln Center theaters that are our home," ABT Executive Director Kara Medoff Barnett told CNBC's "Worldwide Exchange" on Friday. "We know that propecia turkey our New York fans are eager to see ABT's artists take the stage again."ABT just wrapped up a cross-country tour that brought 20 of its 84 dancers, along with 28 support crew, to eight different states. The company performed at outdoor, socially distanced venues, and Barnett said it will be learning from the protocols it developed this summer to ensure a safe season indoors in the fall."We want to continue our commitment to keeping our artists and staff and audiences safe," Barnett said.

"That's certainly what was top of mind when we planned our outdoor tour, keeping audiences outdoors while we have the summer sunshine."Dancers with the American Ballet Theatre perform the company premiere of "La Follia Variations," choreographed by Lauren Lovette and costumes by Victor Glemaud, during a dress rehearsal for the American Ballet Theatre's production of "Uniting in Movement" at the Segerstrom Center for the Arts in Costa Mesa on propecia turkey Thursday, April 22, 2021.Leonard Ortiz | MediaNews Group | Orange County Register via Getty ImagesSince its last fall season in 2019, ABT has had to cancel its in-person performances and shift to digital programming, like many ballet companies across the country and the world.Barnett said the propecia has been a time of adapting and learning for the whole company. "We are always thinking, especially in the past year and a half, what's plan B, plan C," she added. "We are nimble in more ways than one."During the propecia turkey Lincoln Center season, which will take place the last two weeks of October, the performances may require proof of vaccination or a negative hair loss treatment test, depending on guidelines from the Centers for Disease Control and Prevention.

The tickets will be refundable propecia turkey until noon on the day of the performance, in case of any last-minute changes for audience members."We are working very closely with our venues at Lincoln Center. We work very closely with our medical advisor. And we are committed to finding ways we can continue to propecia turkey pursue the mission of this company that has been bringing extraordinary art to audiences for 81 years," Barnett told CNBC.The performances this season will include the classic ballet "Giselle," as well three of the 22 works that were developed over the course of last year while dancers were separated into 11 creative bubbles.

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Barnett isn't worried about the recovery period, saying she's very optimistic about demand for live performance. "I think there is so much pent-up demand for the performing arts, so propecia turkey much pent-up demand for collective activities and experiences and the joy of celebrating together. I actually think we can project that we will have the largest audiences we've seen in years.""We had 6,000 people, 8,000 people in these parks watching ballet under the stars," Barnett added, propecia turkey referencing the cross-country tour.

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And other parts of the world propecia turkey is going to be very helpful in driving policy if and when we do need boosters."The delta variant, already in more than 104 countries, is concerning health officials in the U.S. As they see more breakthrough s, propecia turkey which occur in fully vaccinated people, even though they are more mild.CNBC Health &. Science White House chief medical officer Dr.

Anthony Fauci said fully vaccinated people might want to consider wearing masks indoors as a precaution against the rapidly spreading variant in the U.S.Health experts are concerned about the fall season, when propecia turkey delta is expected to hit states with the lowest vaccination rates the hardest — unless those states and businesses reintroduce mask rules, capacity limits and other public health measures that they've largely rolled back."That's something we obviously don't want to see," Fauci said Wednesday, noting the so-called breakthrough s. "This propecia is clearly different than the propeciaes and the variants that we've had experience with before. It has an extraordinary propecia turkey capability of transmitting from person to person."Dr.

Paul Offit, who advises the FDA on hair loss treatments, said while the treatments still provide excellent protection against severe disease and death, they may not work as well against mild cases or spreading the disease to others.He urged more Americans to get vaccinated, saying propecia turkey delta is a highly contagious propecia and the shots will help people from getting seriously sick. Currently, less than half of the U.S. Population is fully vaccinated, according to data compiled by the CDC."That is a rich and fertile ground for the propecia to continue to reproduce itself and continue to create variants that possibly become more propecia turkey and more resistant to treatments or natural ," he said.WHO officials said Monday that the longer that people around the world remain unvaccinated and social mixing continues, the higher the risk of a more dangerous variant to emerge.The report out of Israel, which began vaccinating its population ahead of many other countries, is likely to bolster arguments from drugmakers that people will eventually need to get booster shots to protect against emerging variants.Pfizer said earlier this month it is starting to see waning immunity from its two-dose treatment, and now plans to seek authorization from the Food and Drug Administration for a booster dose.

However, federal officials say fully vaccinated Americans do not need additional shots at this time.In a statement to CNBC, Pfizer said it remains confident its two-dose regimen is protective against the hair loss and its variants.Still, it said a third dose may be helpful after analysis from its phase three study showed a decline in efficacy against symptomatic after four to six months."Initial data of a third dose of the current treatment demonstrates that a booster dose given at least 6 months after the second dose elicits high neutralization titers against the wild type and the Beta, which are 5 to 10 times higher than after two primary doses," the company said..

NewWave, a full-service Information Technology (IT), business services, and data boots propecia price management company, together with Mathematica, the national Medicaid expert and an insight partner to public and private-sector changemakers, announced today that propecia 1mg tablets price they will partner with the Maryland Department of Health to implement Imersis, their cloud-based data quality tool. Imersis will allow the Maryland Department of Health to dive deep, explore, and refine their Transformed Medicaid Information System (T-MSIS) boots propecia price data. Built on cloud-first architecture, Imersis is a leading-edge Software-as-a-Service (SaaS) which scores files against similar data quality measures as the Centers for Medicare and Medicaid Services (CMS). Imersis decomposes T-MSIS Top Priority Items (TPIs) into data quality measures and allows users to pinpoint specific issues, root out the sources of bad data, and remediate low scores before boots propecia price submitting data files to CMS. NewWave and Mathematica, drawing on their combined extensive experience working with the CMS and their deep knowledge of Medicaid data, are a uniquely suited partnership to support the Maryland Department of Health and improve the data quality of boots propecia price its Medicaid program.

€œThe Imersis tool provides a way for states to visualize their Medicaid data quality and build a strong data analytics program,” said Jay Tanner, NewWave Program Director for Imersis. €œImersis leverages a secure cloud environment and leads with human-centered design (HCD) principles which enables us to ingest T-MSIS data, score it against CMS’s list of Top Priority Items (TPIs), see the scores before submitting to CMS, and make improvements in those areas.” “Imersis is boots propecia price the product of a collaboration which will provide a way for states to leverage advanced data quality analytics and reporting,” said Paul Messino, Senior Researcher and Director of Mathematica’s State Medicaid work. €œI am excited for this opportunity for Mathematica and NewWave to help the Maryland T-MSIS team configure and use Imersis to improve Medicaid data quality for Maryland.” “We view T-MSIS as one of the most important projects which aims to improve data quality and realize better health outcomes through customer service and program integrity - a vision the Department shares with CMS,” said David Wertheimer, Enterprise Architect with the Maryland Department of Health. €œBoth Mathematica and NewWave have demonstrated unparalleled expertise and leadership in T-MSIS and data quality reporting, and we are thrilled to partner with them on this project.”To learn more about Imersis, boots propecia price please visit www.mathematica.org/toolkits/imersis.ContactSarah RodriguezEmail. Sarah.rodriguez@newwave.io Todd Kohlhepp boots propecia price Email.

Tkohlhepp@mathematica-mpr.comMounting real-world evidence shows universal screening for health-related social needs in routine clinical care offers a standardized way for health care providers to identify needs, tailor care, and help patients resolve these needs with referrals to community resources. Yet screening for boots propecia price patients’ social needs can seem like a daunting task for clinical providers. One strategy for providers is to first identify patients’ social needs by administering a screening tool such as the one developed for the Accountable Health Communities Model, a nationwide initiative funded by the Centers for Medicare &. Medicaid Services (CMS) Innovation boots propecia price Center. The model is testing the impact of systematically identifying and addressing health-related social boots propecia price needs among Medicare and Medicaid beneficiaries.

To help providers administer the screening tool, Mathematica developed, on CMS’s behalf, a set of instructions for users called “A Guide to Using the Accountable Health Communities Health-Related Social Needs Screening Tool. Promising Practices and Key Insights.”The Accountable Health Communities Health-Related Social Needs Screening Tool enables users to quickly assess patients’ social needs from five domains that CMS determined as core needs (living situation, food, transportation, utilities, and safety) and eight supplemental domains (financial strain, employment, boots propecia price family and community support, education, physical activity, substance use, mental health, and disabilities). The screening tool is appropriate for use in a wide range of clinical settings, including primary care practices, emergency departments, labor and delivery units, inpatient psychiatric units, behavioral health clinics, and other boots propecia price places where people access clinical care. The tool is available in three versions. (1) a standard self-administered version, (2) a proxy version with questions adapted to enable someone to answer on boots propecia price behalf of the patient, and (3) a multiuse version that includes language for a proxy and for patients answering for themselves.After quickly identifying social needs using the screening tool, health care or social service providers can then connect patients with community resources to address the patients’ unmet needs.Implementing universal health-related social needs screening in clinical settings requires planning, which includes aligning priorities, training staff, and developing customized screening protocols.

In light of this, the guide also includes lessons based on the experiences of organizations participating in the Accountable Health Communities Model. The strategies shared in the guide are meant to inform effective universal screening in a wide range of clinical settings.Promising practices for universal screening described in the guide Cultivate staff buy-in Tailor staffing models to site features Provide dedicated training on screening Use customized scripts to engage patients in screening Consider the timing, location, and process for screening to maximize patients’ participation Anticipate population-specific needs Train staff to manage privacy and address safety concerns Institute continuous quality improvement Prepare staff to respond to common questionsFor more information on the AHC Screening Guide, please contact Lee-Lee Ellis and Rachel Kogan.The American Ballet Theatre — the country's national ballet company — has announced it will be returning to the stage in New York City this October, a year after boots propecia price halting indoor performances due to hair loss treatment."We cannot wait to see ABT in the Lincoln Center theaters that are our home," ABT Executive Director Kara Medoff Barnett told CNBC's "Worldwide Exchange" on Friday. "We know that our New York fans are eager to see ABT's artists take the stage again."ABT just wrapped up boots propecia price a cross-country tour that brought 20 of its 84 dancers, along with 28 support crew, to eight different states. The company performed at outdoor, socially distanced venues, and Barnett said it will be learning from the protocols it developed this summer to ensure a safe season indoors in the fall."We want to continue our commitment to keeping our artists and staff and audiences safe," Barnett said. "That's certainly what was top of mind when we planned our outdoor tour, keeping audiences outdoors while we have the summer sunshine."Dancers with the American Ballet Theatre perform the company premiere of "La Follia Variations," choreographed by Lauren Lovette and costumes by Victor Glemaud, during a dress rehearsal for the American Ballet Theatre's production of "Uniting in Movement" at the Segerstrom Center for the Arts in Costa Mesa on Thursday, April 22, 2021.Leonard Ortiz | boots propecia price MediaNews Group | Orange County Register via Getty ImagesSince its last fall season in 2019, ABT has had to cancel its in-person performances and shift to digital programming, like many ballet companies across the country and the world.Barnett said the propecia has been a time of adapting and learning for the whole company.

"We are always thinking, especially in the past year and a half, what's plan B, plan C," she added. "We are nimble in more ways than one."During the Lincoln Center season, which will take place the last two weeks of October, the performances may require proof of vaccination or a negative boots propecia price hair loss treatment test, depending on guidelines from the Centers for Disease Control and Prevention. The tickets boots propecia price will be refundable until noon on the day of the performance, in case of any last-minute changes for audience members."We are working very closely with our venues at Lincoln Center. We work very closely with our medical advisor. And we are committed to finding ways we can continue to pursue the mission of this company that has been bringing extraordinary art to audiences for 81 years," Barnett told CNBC.The performances this season will include the classic ballet "Giselle," as well boots propecia price three of the 22 works that were developed over the course of last year while dancers were separated into 11 creative bubbles.

"We're bringing three of the works that were created in these residency bubbles to New York audiences to have their live, on-stage premieres," boots propecia price Barnett said. "They've had digital premieres, they've had outdoor premieres around the country — but now, we'll be bringing them to Lincoln Center."The "ABT Across America" performances, which wrapped up Wednesday in New York City, were mostly free. But for a company that saw 36% of its revenue come from ticket sales in 2018, the return of boots propecia price a full program is integral to future success and longevity. Barnett isn't worried about the recovery period, saying she's very optimistic about demand for live performance. "I think there is so much boots propecia price pent-up demand for the performing arts, so much pent-up demand for collective activities and experiences and the joy of celebrating together.

I actually think we can project that we will have the largest audiences we've seen in years.""We had 6,000 people, 8,000 people in these parks watching ballet under the stars," boots propecia price Barnett added, referencing the cross-country tour. "I think that the audiences are ready, they've missed us, and they're eager to come back."People receive a dose of the Pfizer-BioNTech hair loss treatment inside a hair loss treatment mass vaccination center at Rabin Square in Tel Aviv, Israel, on Monday, Jan. 4, 2020.Kobi Wolf | Bloomberg | Getty ImagesPfizer and BioNTech's hair loss treatment is just 39% effective in Israel where the delta variant is the dominant strain, but still provides strong protection against severe illness and hospitalization, according to a new report from the country's Health Ministry.The efficacy figure, which is based on an unspecified number of people between June 20 and July 17, is down from an earlier estimate of 64% two weeks ago and conflicts boots propecia price with data out of the U.K. That found the shot was 88% effective against symptomatic disease caused by the variant.However, the two-dose treatment still works very well in preventing people from getting seriously sick, demonstrating 88% effectiveness against hospitalization and 91% effectiveness against severe illness, according to the Israeli data published Thursday."We have to be mindful that, with time, the effectiveness of these treatments may wane," said Dr. Isaac Bogoch, an infectious disease professor at the University of Toronto.He stressed that the shots are still highly effective in preventing severe , helping hospital systems not get boots propecia price too overwhelmed heading into the colder months.

That being said, "we're still in the hair loss treatment era and anything can happen," he said."We have to be prepared and we have to be nimble boots propecia price that people may need a booster at some point," he added. "This close surveillance that's happening in countries like Israel, the U.K. And other parts of the world is going to be very helpful in driving policy if and when we do need boosters."The delta variant, already in more than 104 countries, is boots propecia price concerning health officials in the U.S. As they see more breakthrough s, which occur in fully boots propecia price vaccinated people, even though they are more mild.CNBC Health &. Science White House chief medical officer Dr.

Anthony Fauci said fully vaccinated people might want to consider wearing masks indoors as a precaution boots propecia price against the rapidly spreading variant in the U.S.Health experts are concerned about the fall season, when delta is expected to hit states with the lowest vaccination rates the hardest — unless those states and businesses reintroduce mask rules, capacity limits and other public health measures that they've largely rolled back."That's something we obviously don't want to see," Fauci said Wednesday, noting the so-called breakthrough s. "This propecia is clearly different than the propeciaes and the variants that we've had experience with before. It has an extraordinary capability boots propecia price of transmitting from person to person."Dr. Paul Offit, boots propecia price who advises the FDA on hair loss treatments, said while the treatments still provide excellent protection against severe disease and death, they may not work as well against mild cases or spreading the disease to others.He urged more Americans to get vaccinated, saying delta is a highly contagious propecia and the shots will help people from getting seriously sick. Currently, less than half of the U.S.

Population is fully vaccinated, according to data compiled by the CDC."That is a rich and fertile ground for the propecia to continue to reproduce itself and continue to create variants that possibly become more and more resistant to treatments or natural ," he said.WHO officials said Monday that the longer that people around the world remain unvaccinated and social mixing continues, the higher the risk of a more dangerous variant to emerge.The report out of Israel, which began vaccinating its population ahead of many other countries, is likely to bolster arguments from drugmakers that people will eventually need to get booster shots to protect against emerging variants.Pfizer said earlier this month it is starting to see waning immunity from its two-dose treatment, and now plans to seek authorization from boots propecia price the Food and Drug Administration for a booster dose. However, federal officials say fully vaccinated Americans do not need additional shots at this time.In a statement to CNBC, Pfizer said it remains confident its two-dose regimen is protective against the hair loss and its variants.Still, it said a third dose may be helpful after analysis from its phase three study showed a decline in efficacy against symptomatic after four to six months."Initial data of a third dose of the current treatment demonstrates that a booster dose given at least 6 months after the second dose elicits high neutralization titers against the wild type and the Beta, which are 5 to 10 times higher than after two primary doses," the company said..

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Over the past 20 years, a large body of research has documented a relationship between higher nurse-to-patient staffing ratios and better patient outcomes, including shorter hospital stays, lower rates of failure to prevent mortality after an in-hospital complication, inpatient mortality for multiple best propecia prices types of patients, hospital-acquired pneumonia, unplanned extubation, respiratory failure and cardiac arrest.1–5 In addition, patients report higher satisfaction when they are cared for in hospitals with higher staffing levels.6 7To date, most studies have not identified an ‘optimal’ nurse staffing ratio,8 which creates a challenge for determining appropriate staffing levels. If increasing nurse staffing always produces at least some improvement in the quality of care, how does one determine what staffing level is best?. This decision is ultimately an economic one, balancing the benefits of nurse staffing with the best propecia prices other options for which those resources could be used. It is in this context that hospitals develop staffing plans, generally based on historical patterns of patient acuity.Practical challenges of nurse staffingHospital staffing plans provide the structure necessary for determining hiring and scheduling, but fall short for a number of reasons.

First, there best propecia prices are multiple ways in which patient acuity can be measured, which can have measurable effects on the staffing levels resulting from acuity models.9 Second, patient volume and acuity can shift rapidly with changes in the volume of admissions, discharges and transfers between units. Third, staffing plans provide little guidance regarding the optimal mix of permanent staff, variable staff and externally contracted staff.The paper by Saville and colleagues10 in this issue of BMJ Quality &. Safety addresses the latter two issues by applying a simulation model to identify the optimal target for baseline nurse staffing in order to minimise periods best propecia prices of understaffing. Included in this model is consideration of the extent to which hospitals should leverage temporary personnel (typically obtained through an external agency) to fill gaps.

The model acknowledges the likelihood that a hospital cannot realistically prevent all shifts from having best propecia prices a shortfall of nurses at all times, as well as the reality that hospital managers lack information about the best balance between permanent and temporary staff. In addition, the analysis includes a calculation of the costs of each staffing approach, drawing from the records of 81 inpatient wards in four hospital organisations.The application of sophisticated simulation models and other advanced analyticl approaches to analysis of nurse staffing has been limited to date, and this paper is an exemplar of the value of such research. Recent studies have used best propecia prices machine learning methods to forecast hospital discharge volume,11 a discrete event simulation model to determine nursing staff needs in a neonatal intensive care unit,12 and a prediction model using machine learning and hierarchical linear regression to link variation in nurse staffing with patient outcomes.13 This new study applied a unique Monte Carlo simulation model to estimate demand for nursing care and test different strategies to meet demand.The results of the analysis are not surprising in that hospitals are much less likely to experience understaffed patient shifts if they aim to have higher baseline staffing. The data demonstrate a notable leftward skew, indicating that hospitals are more likely to have large unanticipated increases in patient volume and acuity than to have unanticipated decreases.

This results in hospitals being more likely to have shifts that are understaffed than shifts that are overstaffed, which inevitably places pressure on hospitals to staff at a higher level and/or have access to best propecia prices a larger pool of temporary nurses. It also is not surprising that hospitals will need to spend more money per patient day if they aim to reduce the percent of shifts that are understaffed. What is surprising about the results is that hospitals do not necessarily achieve cost savings by relying on temporary personnel versus setting regular staffing at a higher level.Trade-offs between permanent and temporary staffThe temporary nursing workforce enables healthcare facilities to maintain flexible yet full care teams based on patient care needs. Hospitals can use temporary nurses to address staffing gaps during leaves of absence, turnover or gaps between recruitment of permanent nurses, as well best propecia prices as during high-census periods.

Temporary personnel are typically more expensive on an hourly basis than permanent staff. In addition, over-reliance on temporary staff can best propecia prices have detrimental effects on permanent nurses’ morale and motivation. Orientations prior to shifts are often limited, which leads to a twofold concern as temporary nurses feel ill-prepared for shifts and permanent staff feel flustered when required to bring the temporary nurse up to speed while being expected to continue normal operations.14 Agency nurses may be assigned to patients and units that are incongruent with their experience and skills—either to unfamiliar units, which affects their ability to confidently deliver care, or to less complex patients where they feel as if their skills are not used adequately.14 15 These issues can create tension between temporary and permanent nursing staff, which can be compounded by the wage disparity. Permanent staff might feel demoralised and expendable when working alongside temporary staff who are not integrated into the social fabric of the staff.16Hospital managers also must be cognisant of the potential quality impact of best propecia prices relying heavily on temporary nursing staff.

Research on the impact of contingent nursing employment on costs and quality have often found negative effects on quality, including mortality, and higher costs.17 18 However, other studies have found that the association between temporary nursing staff and low quality result from general shortages of nursing staff, which make a hospital more likely to employ temporary staff, and not directly from the contingent staff.19–21 Thus, temporary nurses play an important role in alleviating staffing shortages that would otherwise lead to lower quality of care.22Charting a path forward in hospital management and healthcare researchThe maturation of electronic health records and expansion of computerised healthcare management systems provide opportunities both for improved decision making about workforce deployment and for advanced workforce research. In the area of workforce management, nursing and other leaders have a growing array best propecia prices of workforce planning tools available to them. Such tools are most effective when they display clear information about predicted patient needs and staff availability, but managers still must rely on their on-the-ground understanding of their staff and their context of patient care.23 Integration of human resources data with patient outcomes data has revealed that individual nurses and their characteristics have important discrete effects on the quality of care.24 25 Future development of workforce planning tools should translate this evidence to practice. In addition, new technology platforms are emerging to facilitate direct matching between temporary healthcare personnel best propecia prices and healthcare organisations.

One recent study tested a smartphone-based application that allowed for direct matching of locum tenens physicians with a hospital in the English National Health Service, finding that the platform generated benefits including greater transparency and lower cost.26 Similar technologies for registered nurses could facilitate better matching between hospital needs and temporary nurses’ preparedness to meet those needs.Analytical methods that fully leverage the large datasets compiled through electronic health records, human resources systems and other sources can be applied to advance research on the composition of nursing teams to improve quality of care. As noted above, prior research has applied machine learning and discrete event simulation best propecia prices to analyses of healthcare staffing. Other recent studies have leveraged natural language processing of nursing notes to identify fall risk factors27 and applied data mining of human resources records to understand the job titles held by nurses.28 Linking these rapidly advancing analytical approaches that assess the outcomes and costs of nurse staffing strategies, such as the work by Saville and colleagues published in this issue, to data on the impact of nurse staffing on the long-term costs of patient care will further advance the capacity of hospital leaders to design cost-effective policies for workforce deployment.Guidelines aim to align clinical care with best practice. However, simply publishing a guideline rarely triggers behavioural changes to match guideline recommendations.1–3 We thus transform guideline recommendations into actionable tasks by introducing interventions that promote behavioural changes meant to produce guideline-concordant care.

Unfortunately, not much has changed in the 25 years since Oxman and colleagues concluded that we have no ‘magic bullets’ when it comes to changing clinician behaviour.4 In fact, far from magic bullets, interventions aimed at increasing the best propecia prices degree to which patients receive care recommended in guidelines (eg, educational interventions, reminders, audit and feedback, financial incentives, computerised decision support) typically produce disappointingly small improvements in care.5–10Much improvement work aims to ‘make the right thing to do the easy thing to do.’ Yet, design solutions which hardwire the desired actions remain few and far between. Further, improvement interventions which ‘softwire’ such actions—not guaranteeing that they occur, but at least increasing the likelihood that clinicians will deliver the care recommended in guidelines—mostly produce small improvements.5–9 Until this situation changes, we need to acknowledge the persistent reality that guidelines themselves represent a main strategy for promoting care consistent with current evidence, which means their design should promote the desired actions.11 12In this respect, guidelines constitute a type of clinical decision support. And, like best propecia prices all decision support interventions, guidelines require. (1) user testing to assess if the content is understood as intended and (2) empirical testing to assess if the decision support provided by the guideline does in fact promote the desired behaviours.

While the processes for developing guidelines have received substantial attention over best propecia prices the years,13–18 surprisingly little attention has been paid to empirically answering basic questions about the finished product. Do users understand guidelines as intended?. And, what version of a given guideline engenders the desired behaviours by best propecia prices clinicians?. In this issue of BMJ Quality and Safety, Jones et al19 address this gap by using simulation to compare the frequency of medication errors when clinicians administer an intravenous medication using an existing guideline in the UK’s National Health Service (NHS) versus a revised and user-tested version of the guideline that more clearly promotes the desired actions.

Their findings demonstrate that changes to guideline design (through addition of actionable best propecia prices decision supports) based on user feedback does in fact trigger changes in behaviour that can improve safety. This is an exciting use of simulation, which we believe should encourage further studies in this vein.Ensuring end users understand and use guidelines as intendedJones and colleagues’ approach affords an opportunity to reflect on the benefits of user testing and simulation of guidelines. The design and evaluation of their revised guidelines provides an excellent example of a careful stepwise progression in the development and evaluation of a guideline as a type of decision support for best propecia prices clinicians. First, in a prior study,20 they user tested the original NHS guidelines to improve retrieval and comprehension of information.

The authors produced a revised guideline, which included reformatted sections as well as increased support for key calculations, such as for infusion rates. The authors again user tested the best propecia prices revised guideline, successfully showing higher rates of comprehension. Note that user testing refers to a specific approach focused on comprehension rather than behaviour21 and is distinct from usability testing. Second, in the current study, Jones et al evaluated whether nurse and midwife end users exhibited the desired behavioural changes when given the best propecia prices revised guidelines (with addition of actionable decision supports), compared with a control group working with the current version of the guidelines used in practice.

As a result, Jones and colleagues verify that end users (1) understand the content in the guideline and (2) actually change their behaviour in response to using it.Simulation can play a particularly useful role in this context, as it can help identify problems with users’ comprehension of the guideline and also empirically assess what behavioural changes occur in response to design changes in the guidelines. The level of methodological control and qualitative detail that simulation provides is difficult to feasibly replicate with real-world pilot studies, and therefore simulation fills a critical gap.Jones et al report best propecia prices successful changes in behaviour due to the revised guidelines in which they added actionable decision supports. For example, their earlier user testing found that participants using the initial guidelines did not account for displacement volume when reconstituting the powdered drug, leading to dosing errors. A second error with the initial guidelines best propecia prices involved participants using the shortest infusion rate provided (eg, guidelines state ‘1 to 3 hours’), without realising that the shortest rate is not appropriate for certain doses (eg, 1 hour is appropriate for smaller doses, but larger doses should not be infused over 1 hour because the drug would then be administered faster than the maximum allowable infusion rate of 3 mg/kg/hour).

These two issues were addressed in the revised guidelines by providing key determinants for ‘action’ such as calculation formulas that account for displacement volume and infusion duration, thereby more carefully guiding end users to avoid these dose and rate errors. These changes to the guideline triggered specific behaviours (eg, best propecia prices calculations that account for all variables) that did not occur with the initial guidelines. Therefore, the simulation testing demonstrated the value of providing determinants for action, such as specific calculation formulas to support end users, by showing a clear reduction in dose and rate errors when using the revised guidelines compared with the initial guidelines.The authors also report that other types of medication-specific errors remained unaffected by the revised guidelines (eg, incorrect technique and flush errors)—the changes made did not facilitate the desired actions. The initial guidelines indicate ‘DO NOT SHAKE’ in capital letters, and there is a section specific best propecia prices to ‘Flushing’.

In contrast, the revised guidelines do not capitalise the warning about shaking the vial, but embed the warning with a numbered sequence in the medication preparation section, aiming to increase the likelihood of reading it at the appropriate time. The revised guidelines do not have a section specific to flushing, but embed the flushing instructions as an unnumbered step in the administration section. Thus, the value of embedding technique and flushing information within the context of use was not validated in the simulation testing (ie, no significant differences in the rates of these errors), highlighting precisely the best propecia prices pivotal role that simulation can play in assessing whether attempts to improve usability result in actual behavioural changes.Finally, simulation can identify potential unintended consequences of a guideline. For instance, Jones and colleagues observed an increase in errors (although not statistically significant) that were not medication specific (eg, non-aseptic technique such as hand washing, swabbing vials with an alcohol wipe).

Given that the revised guidelines were specific to the medication tested, it is unusual that we see a tendency best propecia prices toward a worsening effect on generic medication preparation skills. Again, this finding was not significant, but we highlight this to remind ourselves of the very real possibility that some interventions might introduce new and unexpected errors in response to changing workflow and practice6. Simulations offer an opportunity best propecia prices to spot these risks in advance.Now that Jones et al have seen how the revised guidelines change behaviour, they are optimally positioned to move forward. On one hand, they have the option of revising the guidelines further in attempts to address these resistant errors, and on the other, they can consider designing other interventions to be implemented in parallel with their user-tested guidance.

At first glance, the errors that best propecia prices were resistant to change appear to be mechanical tasks that end users might think of as applying uniformly to multiple medications (eg, flush errors, non-aseptic technique). Therefore, a second intervention that has a more general scope (rather than drug specific) might be pursued. Regardless of what they decide to pursue, we applaud their measured approach and highlight that the key takeaway is that their next steps are supported with clearer evidence of what to expect when the guidelines are released—certainly a helpful piece of information to guide decisions as to whether broad implementation of guidelines is justified.Caveats and conclusionSimulation is not a panacea—it is best propecia prices not able to assess longitudinal adherence, and there are limitations to how realistically clinicians behave when observed for a few sample procedures when under the scrutiny of observers. Further, studies where interventions are implemented to assess whether they move the needle on the outcomes we care about (eg, adverse events, length of stay, patient mortality) are needed and should continue.

However, having end users physically perform clinical tasks with the intervention in representative environments represents best propecia prices an important strategy to assess the degree to which guidelines and other decision support interventions in fact promote the desired behaviours and to spot problems in advance of implementation. Such simulation testing is not currently a routine step in intervention design. We hope it becomes a more common phenomenon, with more improvement work following the example of the approach so effectively demonstrated by Jones and colleagues..

Over the past 20 years, a large body of research has documented a boots propecia price relationship between higher nurse-to-patient staffing ratios and better patient outcomes, including shorter hospital stays, lower rates of failure to prevent mortality after an in-hospital complication, inpatient mortality for multiple types of patients, hospital-acquired pneumonia, unplanned extubation, respiratory failure and cardiac arrest.1–5 In addition, patients report higher satisfaction when they are cared for in hospitals with higher staffing levels.6 7To date, most studies have not identified an ‘optimal’ nurse staffing ratio,8 which creates a challenge for determining appropriate staffing levels. If increasing nurse staffing always produces at least some improvement in the quality of care, how does one determine what staffing level is best?. This decision is ultimately an economic one, balancing the benefits of nurse staffing boots propecia price with the other options for which those resources could be used. It is in this context that hospitals develop staffing plans, generally based on historical patterns of patient acuity.Practical challenges of nurse staffingHospital staffing plans provide the structure necessary for determining hiring and scheduling, but fall short for a number of reasons.

First, there boots propecia price are multiple ways in which patient acuity can be measured, which can have measurable effects on the staffing levels resulting from acuity models.9 Second, patient volume and acuity can shift rapidly with changes in the volume of admissions, discharges and transfers between units. Third, staffing plans provide little guidance regarding the optimal mix of permanent staff, variable staff and externally contracted staff.The paper by Saville and colleagues10 in this issue of BMJ Quality &. Safety addresses the latter two issues by applying a simulation model boots propecia price to identify the optimal target for baseline nurse staffing in order to minimise periods of understaffing. Included in this model is consideration of the extent to which hospitals should leverage temporary personnel (typically obtained through an external agency) to fill gaps.

The model acknowledges boots propecia price the likelihood that a hospital cannot realistically prevent all shifts from having a shortfall of nurses at all times, as well as the reality that hospital managers lack information about the best balance between permanent and temporary staff. In addition, the analysis includes a calculation of the costs of each staffing approach, drawing from the records of 81 inpatient wards in four hospital organisations.The application of sophisticated simulation models and other advanced analyticl approaches to analysis of nurse staffing has been limited to date, and this paper is an exemplar of the value of such research. Recent studies have used machine learning methods to forecast hospital discharge volume,11 a discrete event simulation model to determine nursing staff needs in a neonatal intensive care unit,12 and a prediction model using machine learning and hierarchical linear regression to link variation in nurse staffing with patient boots propecia price outcomes.13 This new study applied a unique Monte Carlo simulation model to estimate demand for nursing care and test different strategies to meet demand.The results of the analysis are not surprising in that hospitals are much less likely to experience understaffed patient shifts if they aim to have higher baseline staffing. The data demonstrate a notable leftward skew, indicating that hospitals are more likely to have large unanticipated increases in patient volume and acuity than to have unanticipated decreases.

This results in hospitals being more likely to have shifts that are understaffed than shifts that are overstaffed, which inevitably places pressure on hospitals to staff at a higher level and/or have access boots propecia price to a larger pool of temporary nurses. It also is not surprising that hospitals will need to spend more money per patient day if they aim to reduce the percent of shifts that are understaffed. What is surprising about the results is that hospitals do not necessarily achieve cost savings by relying on temporary personnel versus setting regular staffing at a higher level.Trade-offs between permanent and temporary staffThe temporary nursing workforce enables healthcare facilities to maintain flexible yet full care teams based on patient care needs. Hospitals can use temporary nurses to address staffing gaps during leaves of absence, turnover boots propecia price or gaps between recruitment of permanent nurses, as well as during high-census periods.

Temporary personnel are typically more expensive on an hourly basis than permanent staff. In addition, boots propecia price over-reliance on temporary staff can have detrimental effects on permanent nurses’ morale and motivation. Orientations prior to shifts are often limited, which leads to a twofold concern as temporary nurses feel ill-prepared for shifts and permanent staff feel flustered when required to bring the temporary nurse up to speed while being expected to continue normal operations.14 Agency nurses may be assigned to patients and units that are incongruent with their experience and skills—either to unfamiliar units, which affects their ability to confidently deliver care, or to less complex patients where they feel as if their skills are not used adequately.14 15 These issues can create tension between temporary and permanent nursing staff, which can be compounded by the wage disparity. Permanent staff might feel demoralised and boots propecia price expendable when working alongside temporary staff who are not integrated into the social fabric of the staff.16Hospital managers also must be cognisant of the potential quality impact of relying heavily on temporary nursing staff.

Research on the impact of contingent nursing employment on costs and quality have often found negative effects on quality, including mortality, and higher costs.17 18 However, other studies have found that the association between temporary nursing staff and low quality result from general shortages of nursing staff, which make a hospital more likely to employ temporary staff, and not directly from the contingent staff.19–21 Thus, temporary nurses play an important role in alleviating staffing shortages that would otherwise lead to lower quality of care.22Charting a path forward in hospital management and healthcare researchThe maturation of electronic health records and expansion of computerised healthcare management systems provide opportunities both for improved decision making about workforce deployment and for advanced workforce research. In the area of workforce boots propecia price management, nursing and other leaders have a growing array of workforce planning tools available to them. Such tools are most effective when they display clear information about predicted patient needs and staff availability, but managers still must rely on their on-the-ground understanding of their staff and their context of patient care.23 Integration of human resources data with patient outcomes data has revealed that individual nurses and their characteristics have important discrete effects on the quality of care.24 25 Future development of workforce planning tools should translate this evidence to practice. In addition, boots propecia price new technology platforms are emerging to facilitate direct matching between temporary healthcare personnel and healthcare organisations.

One recent study tested a smartphone-based application that allowed for direct matching of locum tenens physicians with a hospital in the English National Health Service, finding that the platform generated benefits including greater transparency and lower cost.26 Similar technologies for registered nurses could facilitate better matching between hospital needs and temporary nurses’ preparedness to meet those needs.Analytical methods that fully leverage the large datasets compiled through electronic health records, human resources systems and other sources can be applied to advance research on the composition of nursing teams to improve quality of care. As noted above, prior research has applied machine learning and discrete event simulation to boots propecia price analyses of healthcare staffing. Other recent studies have leveraged natural language processing of nursing notes to identify fall risk factors27 and applied data mining of human resources records to understand the job titles held by nurses.28 Linking these rapidly advancing analytical approaches that assess the outcomes and costs of nurse staffing strategies, such as the work by Saville and colleagues published in this issue, to data on the impact of nurse staffing on the long-term costs of patient care will further advance the capacity of hospital leaders to design cost-effective policies for workforce deployment.Guidelines aim to align clinical care with best practice. However, simply publishing a guideline rarely triggers behavioural changes to match guideline recommendations.1–3 We thus transform guideline recommendations into actionable tasks by introducing interventions that promote behavioural changes meant to produce guideline-concordant care.

Unfortunately, not much has changed in the 25 years since Oxman and colleagues concluded that we have no ‘magic bullets’ when it comes to changing clinician behaviour.4 In fact, far from magic bullets, interventions aimed at boots propecia price increasing the degree to which patients receive care recommended in guidelines (eg, educational interventions, reminders, audit and feedback, financial incentives, computerised decision support) typically produce disappointingly small improvements in care.5–10Much improvement work aims to ‘make the right thing to do the easy thing to do.’ Yet, design solutions which hardwire the desired actions remain few and far between. Further, improvement interventions which ‘softwire’ such actions—not guaranteeing that they occur, but at least increasing the likelihood that clinicians will deliver the care recommended in guidelines—mostly produce small improvements.5–9 Until this situation changes, we need to acknowledge the persistent reality that guidelines themselves represent a main strategy for promoting care consistent with current evidence, which means their design should promote the desired actions.11 12In this respect, guidelines constitute a type of clinical decision support. And, like all decision support interventions, guidelines boots propecia price require. (1) user testing to assess if the content is understood as intended and (2) empirical testing to assess if the decision support provided by the guideline does in fact promote the desired behaviours.

While the boots propecia price processes for developing guidelines have received substantial attention over the years,13–18 surprisingly little attention has been paid to empirically answering basic questions about the finished product. Do users understand guidelines as intended?. And, what version of boots propecia price a given guideline engenders the desired behaviours by clinicians?. In this issue of BMJ Quality and Safety, Jones et al19 address this gap by using simulation to compare the frequency of medication errors when clinicians administer an intravenous medication using an existing guideline in the UK’s National Health Service (NHS) versus a revised and user-tested version of the guideline that more clearly promotes the desired actions.

Their findings demonstrate that changes to guideline design (through addition of boots propecia price actionable decision supports) based on user feedback does in fact trigger changes in behaviour that can improve safety. This is an exciting use of simulation, which we believe should encourage further studies in this vein.Ensuring end users understand and use guidelines as intendedJones and colleagues’ approach affords an opportunity to reflect on the benefits of user testing and simulation of guidelines. The design and evaluation of their revised guidelines provides an excellent example of a careful stepwise progression in the development and evaluation of a guideline boots propecia price as a type of decision support for clinicians. First, in a prior study,20 they user tested the original NHS guidelines to improve retrieval and comprehension of information.

The authors produced a revised guideline, which included reformatted sections as well as increased support for key calculations, such as for infusion rates. The authors again user tested the revised boots propecia price guideline, successfully showing higher rates of comprehension. Note that user testing refers to a specific approach focused on comprehension rather than behaviour21 and is distinct from usability testing. Second, in the current study, Jones et al evaluated whether nurse and midwife end boots propecia price users exhibited the desired behavioural changes when given the revised guidelines (with addition of actionable decision supports), compared with a control group working with the current version of the guidelines used in practice.

As a result, Jones and colleagues verify that end users (1) understand the content in the guideline and (2) actually change their behaviour in response to using it.Simulation can play a particularly useful role in this context, as it can help identify problems with users’ comprehension of the guideline and also empirically assess what behavioural changes occur in response to design changes in the guidelines. The level of methodological control and qualitative detail that simulation provides is difficult to boots propecia price feasibly replicate with real-world pilot studies, and therefore simulation fills a critical gap.Jones et al report successful changes in behaviour due to the revised guidelines in which they added actionable decision supports. For example, their earlier user testing found that participants using the initial guidelines did not account for displacement volume when reconstituting the powdered drug, leading to dosing errors. A second boots propecia price error with the initial guidelines involved participants using the shortest infusion rate provided (eg, guidelines state ‘1 to 3 hours’), without realising that the shortest rate is not appropriate for certain doses (eg, 1 hour is appropriate for smaller doses, but larger doses should not be infused over 1 hour because the drug would then be administered faster than the maximum allowable infusion rate of 3 mg/kg/hour).

These two issues were addressed in the revised guidelines by providing key determinants for ‘action’ such as calculation formulas that account for displacement volume and infusion duration, thereby more carefully guiding end users to avoid these dose and rate errors. These changes to the boots propecia price guideline triggered specific behaviours (eg, calculations that account for all variables) that did not occur with the initial guidelines. Therefore, the simulation testing demonstrated the value of providing determinants for action, such as specific calculation formulas to support end users, by showing a clear reduction in dose and rate errors when using the revised guidelines compared with the initial guidelines.The authors also report that other types of medication-specific errors remained unaffected by the revised guidelines (eg, incorrect technique and flush errors)—the changes made did not facilitate the desired actions. The initial guidelines indicate ‘DO boots propecia price NOT SHAKE’ in capital letters, and there is a section specific to ‘Flushing’.

In contrast, the revised guidelines do not capitalise the warning about shaking the vial, but embed the warning with a numbered sequence in the medication preparation section, aiming to increase the likelihood of reading it at the appropriate time. The revised guidelines do not have a section specific to flushing, but embed the flushing instructions as an unnumbered step in the administration section. Thus, the boots propecia price value of embedding technique and flushing information within the context of use was not validated in the simulation testing (ie, no significant differences in the rates of these errors), highlighting precisely the pivotal role that simulation can play in assessing whether attempts to improve usability result in actual behavioural changes.Finally, simulation can identify potential unintended consequences of a guideline. For instance, Jones and colleagues observed an increase in errors (although not statistically significant) that were not medication specific (eg, non-aseptic technique such as hand washing, swabbing vials with an alcohol wipe).

Given that the revised guidelines were specific to the medication tested, it is unusual that we see a tendency boots propecia price toward a worsening effect on generic medication preparation skills. Again, this finding was not significant, but we highlight this to remind ourselves of the very real possibility that some interventions might introduce new and unexpected errors in response to changing workflow and practice6. Simulations offer an opportunity to spot these risks in boots propecia price advance.Now that Jones et al have seen how the revised guidelines change behaviour, they are optimally positioned to move forward. On one hand, they have the option of revising the guidelines further in attempts to address these resistant errors, and on the other, they can consider designing other interventions to be implemented in parallel with their user-tested guidance.

At first glance, the errors that were resistant to change appear to be mechanical boots propecia price tasks that end users might think of as applying uniformly to multiple medications (eg, flush errors, non-aseptic technique). Therefore, a second intervention that has a more general scope (rather than drug specific) might be pursued. Regardless of boots propecia price what they decide to pursue, we applaud their measured approach and highlight that the key takeaway is that their next steps are supported with clearer evidence of what to expect when the guidelines are released—certainly a helpful piece of information to guide decisions as to whether broad implementation of guidelines is justified.Caveats and conclusionSimulation is not a panacea—it is not able to assess longitudinal adherence, and there are limitations to how realistically clinicians behave when observed for a few sample procedures when under the scrutiny of observers. Further, studies where interventions are implemented to assess whether they move the needle on the outcomes we care about (eg, adverse events, length of stay, patient mortality) are needed and should continue.

However, having end users physically perform clinical tasks with the intervention in representative environments represents an important strategy to assess the degree to which guidelines and other decision support interventions in fact promote the desired behaviours and to spot problems boots propecia price in advance of implementation. Such simulation testing is not currently a routine step in intervention design. We hope it becomes a more common phenomenon, with more improvement work following the example of the approach so effectively demonstrated by Jones and colleagues..